BDBM50108913 CHEMBL3596595

SMILES: NC(=O)c1ccc(F)c(c1)-c1ccc2N(CCCc2c1)C(=O)c1c(F)cccc1Cl

InChI Key: InChIKey=JDPDWBZZIQXSOP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50108913   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM50108913 (CHEMBL3596595) Show SMILES NC(=O)c1ccc(F)c(c1)-c1ccc2N(CCCc2c1)C(=O)c1c(F)cccc1Cl Show InChI InChI=1S/C23H17ClF2N2O2/c24-17-4-1-5-19(26)21(17)23(30)28-10-2-3-14-11-13(7-9-20(14)28)16-12-15(22(27)29)6-8-18(16)25/h1,4-9,11-12H,2-3,10H2,(H2,27,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec Inc. Curated by ChEMBL					Assay Description Inverse agonist activity at human recombinant GST-tagged RORgammat ligand binding domain assessed as effect on receptor-biotin tagged TRAP220 co-acti...				Bioorg Med Chem Lett 25: 2991-7 (2015) BindingDB Entry DOI: 10.7270/Q2ZP47XQ
					More data for this Ligand-Target Pair