BDBM50108923 CHEMBL3596610

SMILES: CC1CCc2cc(ccc2N1C(=O)c1c(F)cccc1Cl)-c1cc(ccc1Cl)C(N)=O

InChI Key: InChIKey=PEXFKQPHYOPFPY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50108923   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM50108923 (CHEMBL3596610) Show SMILES CC1CCc2cc(ccc2N1C(=O)c1c(F)cccc1Cl)-c1cc(ccc1Cl)C(N)=O Show InChI InChI=1S/C24H19Cl2FN2O2/c1-13-5-6-15-11-14(17-12-16(23(28)30)7-9-18(17)25)8-10-21(15)29(13)24(31)22-19(26)3-2-4-20(22)27/h2-4,7-13H,5-6H2,1H3,(H2,28,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec Inc. Curated by ChEMBL					Assay Description Inverse agonist activity at human recombinant GST-tagged RORgammat ligand binding domain assessed as effect on receptor-biotin tagged TRAP220 co-acti...				Bioorg Med Chem Lett 25: 2991-7 (2015) BindingDB Entry DOI: 10.7270/Q2ZP47XQ
					More data for this Ligand-Target Pair