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SMILES: NC(=O)c1ccc(Cl)c(c1)-c1ccc2N(CCC(F)(F)c2c1)C(=O)c1c(F)cccc1Cl

InChI Key: InChIKey=SCUQRQCKOSKVFL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50108924   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))		BDBM50108924
PNG
(CHEMBL3596613)
Show SMILES NC(=O)c1ccc(Cl)c(c1)-c1ccc2N(CCC(F)(F)c2c1)C(=O)c1c(F)cccc1Cl
Show InChI InChI=1S/C23H15Cl2F3N2O2/c24-16-6-4-13(21(29)31)10-14(16)12-5-7-19-15(11-12)23(27,28)8-9-30(19)22(32)20-17(25)2-1-3-18(20)26/h1-7,10-11H,8-9H2,(H2,29,31)
PDB

UniProtKB/SwissProt

antibodypedia
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AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 3.60E+3n/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant GST-tagged RORgammat ligand binding domain assessed as effect on receptor-biotin tagged TRAP220 co-acti...

Bioorg Med Chem Lett 25: 2991-7 (2015)


BindingDB Entry DOI: 10.7270/Q2ZP47XQ
More data for this
Ligand-Target Pair