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BDBM50108926 CHEMBL3596626

SMILES: CCN(C(=O)c1c(F)cccc1Cl)c1ccc(cc1C(F)(F)F)-c1cc(ccc1Cl)C(N)=O

InChI Key: InChIKey=MOUPNQGUWGJJCO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50108926   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear receptor ROR-gamma (RORC)


(Homo sapiens (Human))		BDBM50108926
PNG
(CHEMBL3596626)
Show SMILES CCN(C(=O)c1c(F)cccc1Cl)c1ccc(cc1C(F)(F)F)-c1cc(ccc1Cl)C(N)=O
Show InChI InChI=1S/C23H16Cl2F4N2O2/c1-2-31(22(33)20-17(25)4-3-5-18(20)26)19-9-7-12(11-15(19)23(27,28)29)14-10-13(21(30)32)6-8-16(14)24/h3-11H,2H2,1H3,(H2,30,32)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
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AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant GST-tagged RORgammat ligand binding domain assessed as effect on receptor-biotin tagged TRAP220 co-acti...

Bioorg Med Chem Lett 25: 2991-7 (2015)


BindingDB Entry DOI: 10.7270/Q2ZP47XQ
More data for this
Ligand-Target Pair