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SMILES: Clc1cnc(NC(=O)c2cc[nH]n2)s1

InChI Key: InChIKey=UPADZLUUCMMKJN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50109561   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50109561 (CHEMBL3604139) Show SMILES Clc1cnc(NC(=O)c2cc[nH]n2)s1 Show InChI InChI=1S/C7H5ClN4OS/c8-5-3-9-7(14-5)11-6(13)4-1-2-10-12-4/h1-3H,(H,10,12)(H,9,11,13)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...				Bioorg Med Chem Lett 25: 3024-9 (2015) BindingDB Entry DOI: 10.7270/Q2R21350
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50109561 (CHEMBL3604139) Show SMILES Clc1cnc(NC(=O)c2cc[nH]n2)s1 Show InChI InChI=1S/C7H5ClN4OS/c8-5-3-9-7(14-5)11-6(13)4-1-2-10-12-4/h1-3H,(H,10,12)(H,9,11,13)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	384	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...				Bioorg Med Chem Lett 25: 3024-9 (2015) BindingDB Entry DOI: 10.7270/Q2R21350
					More data for this Ligand-Target Pair