BDBM50109681 2-(2,6-Dichloro-3-methyl-phenylamino)-N-(2-methoxy-ethyl)-benzamide::CHEMBL149775

SMILES: COCCNC(=O)c1ccccc1Nc1c(Cl)ccc(C)c1Cl

InChI Key: InChIKey=NMMUPISIPKSYHD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50109681   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50109681 (2-(2,6-Dichloro-3-methyl-phenylamino)-N-(2-methoxy...) Show SMILES COCCNC(=O)c1ccccc1Nc1c(Cl)ccc(C)c1Cl Show InChI InChI=1S/C17H18Cl2N2O2/c1-11-7-8-13(18)16(15(11)19)21-14-6-4-3-5-12(14)17(22)20-9-10-23-2/h3-8,21H,9-10H2,1-2H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Inhibition of the human Prostaglandin G/H synthase 2 was determined by thin-layer chromatography assay				Bioorg Med Chem Lett 12: 521-4 (2002) BindingDB Entry DOI: 10.7270/Q2BP0247
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase) (Ovis aries (Sheep))	BDBM50109681 (2-(2,6-Dichloro-3-methyl-phenylamino)-N-(2-methoxy...) Show SMILES COCCNC(=O)c1ccccc1Nc1c(Cl)ccc(C)c1Cl Show InChI InChI=1S/C17H18Cl2N2O2/c1-11-7-8-13(18)16(15(11)19)21-14-6-4-3-5-12(14)17(22)20-9-10-23-2/h3-8,21H,9-10H2,1-2H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Inhibition of the ovine Prostaglandin G/H synthase 1 was determined by thin-layer chromatography assay				Bioorg Med Chem Lett 12: 521-4 (2002) BindingDB Entry DOI: 10.7270/Q2BP0247
					More data for this Ligand-Target Pair