BDBM50109942 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-phenyl-pyrazolo[1,5-a]pyridine::CHEMBL155913

SMILES: Clc1ccc(cc1)N1CCN(Cc2cnn3c(cccc23)-c2ccccc2)CC1

InChI Key: InChIKey=XDYCBVKXSXIDCW-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50109942   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50109942 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-phe...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cnn3c(cccc23)-c2ccccc2)CC1 Show InChI InChI=1S/C24H23ClN4/c25-21-9-11-22(12-10-21)28-15-13-27(14-16-28)18-20-17-26-29-23(7-4-8-24(20)29)19-5-2-1-3-6-19/h1-12,17H,13-16,18H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D4 stably expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50109942 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-phe...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cnn3c(cccc23)-c2ccccc2)CC1 Show InChI InChI=1S/C24H23ClN4/c25-21-9-11-22(12-10-21)28-15-13-27(14-16-28)18-20-17-26-29-23(7-4-8-24(20)29)19-5-2-1-3-6-19/h1-12,17H,13-16,18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D3 stably expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
DRD1 (BOVINE)	BDBM50109942 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-phe...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cnn3c(cccc23)-c2ccccc2)CC1 Show InChI InChI=1S/C24H23ClN4/c25-21-9-11-22(12-10-21)28-15-13-27(14-16-28)18-20-17-26-29-23(7-4-8-24(20)29)19-5-2-1-3-6-19/h1-12,17H,13-16,18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D1 stably expressed in CHO cells by [3H]-SCH- 23390 displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109942 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-phe...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cnn3c(cccc23)-c2ccccc2)CC1 Show InChI InChI=1S/C24H23ClN4/c25-21-9-11-22(12-10-21)28-15-13-27(14-16-28)18-20-17-26-29-23(7-4-8-24(20)29)19-5-2-1-3-6-19/h1-12,17H,13-16,18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D2 (short) stably expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109942 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-phe...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cnn3c(cccc23)-c2ccccc2)CC1 Show InChI InChI=1S/C24H23ClN4/c25-21-9-11-22(12-10-21)28-15-13-27(14-16-28)18-20-17-26-29-23(7-4-8-24(20)29)19-5-2-1-3-6-19/h1-12,17H,13-16,18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D2 (long) stably expressed in CHO cells by [3H]-Spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair