BDBM50109944 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-ethynyl-2-methyl-pyrazolo[1,5-a]pyridine::CHEMBL156851

SMILES: Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)C#C

InChI Key: InChIKey=RZAVUFOOSFLHIY-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50109944   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50109944 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-eth...) Show SMILES Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)C#C Show InChI InChI=1S/C21H21ClN4/c1-3-18-5-4-6-21-20(16(2)23-26(18)21)15-24-11-13-25(14-12-24)19-9-7-17(22)8-10-19/h1,4-10H,11-15H2,2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D4 stably expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
DRD1 (BOVINE)	BDBM50109944 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-eth...) Show SMILES Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)C#C Show InChI InChI=1S/C21H21ClN4/c1-3-18-5-4-6-21-20(16(2)23-26(18)21)15-24-11-13-25(14-12-24)19-9-7-17(22)8-10-19/h1,4-10H,11-15H2,2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D1 stably expressed in CHO cells by [3H]-SCH- 23390 displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50109944 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-eth...) Show SMILES Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)C#C Show InChI InChI=1S/C21H21ClN4/c1-3-18-5-4-6-21-20(16(2)23-26(18)21)15-24-11-13-25(14-12-24)19-9-7-17(22)8-10-19/h1,4-10H,11-15H2,2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D3 stably expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109944 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-eth...) Show SMILES Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)C#C Show InChI InChI=1S/C21H21ClN4/c1-3-18-5-4-6-21-20(16(2)23-26(18)21)15-24-11-13-25(14-12-24)19-9-7-17(22)8-10-19/h1,4-10H,11-15H2,2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D2 (long) stably expressed in CHO cells by [3H]-Spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109944 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-eth...) Show SMILES Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)C#C Show InChI InChI=1S/C21H21ClN4/c1-3-18-5-4-6-21-20(16(2)23-26(18)21)15-24-11-13-25(14-12-24)19-9-7-17(22)8-10-19/h1,4-10H,11-15H2,2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D2 (short) stably expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair