BDBM50109946 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-2-methyl-7-phenyl-pyrazolo[1,5-a]pyridine::CHEMBL351550

SMILES: Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)-c1ccccc1

InChI Key: InChIKey=JQBYEGVGELAAOI-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50109946   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50109946 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-2-met...) Show SMILES Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)-c1ccccc1 Show InChI InChI=1S/C25H25ClN4/c1-19-23(18-28-14-16-29(17-15-28)22-12-10-21(26)11-13-22)25-9-5-8-24(30(25)27-19)20-6-3-2-4-7-20/h2-13H,14-18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D4 stably expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50109946 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-2-met...) Show SMILES Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)-c1ccccc1 Show InChI InChI=1S/C25H25ClN4/c1-19-23(18-28-14-16-29(17-15-28)22-12-10-21(26)11-13-22)25-9-5-8-24(30(25)27-19)20-6-3-2-4-7-20/h2-13H,14-18H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D3 stably expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
DRD1 (BOVINE)	BDBM50109946 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-2-met...) Show SMILES Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)-c1ccccc1 Show InChI InChI=1S/C25H25ClN4/c1-19-23(18-28-14-16-29(17-15-28)22-12-10-21(26)11-13-22)25-9-5-8-24(30(25)27-19)20-6-3-2-4-7-20/h2-13H,14-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D1 stably expressed in CHO cells by [3H]-SCH- 23390 displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109946 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-2-met...) Show SMILES Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)-c1ccccc1 Show InChI InChI=1S/C25H25ClN4/c1-19-23(18-28-14-16-29(17-15-28)22-12-10-21(26)11-13-22)25-9-5-8-24(30(25)27-19)20-6-3-2-4-7-20/h2-13H,14-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D2 (short) stably expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109946 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-2-met...) Show SMILES Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)-c1ccccc1 Show InChI InChI=1S/C25H25ClN4/c1-19-23(18-28-14-16-29(17-15-28)22-12-10-21(26)11-13-22)25-9-5-8-24(30(25)27-19)20-6-3-2-4-7-20/h2-13H,14-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D2 (long) stably expressed in CHO cells by [3H]-Spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair