BDBM50109949 7-(4-Benzyl-piperazin-1-yl)-3-[4-(4-chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine::CHEMBL160266

SMILES: Clc1ccc(cc1)N1CCN(Cc2cnn3c(cccc23)N2CCN(Cc3ccccc3)CC2)CC1

InChI Key: InChIKey=GYWHDZIJHYATFG-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50109949   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50109949 (7-(4-Benzyl-piperazin-1-yl)-3-[4-(4-chloro-phenyl)...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cnn3c(cccc23)N2CCN(Cc3ccccc3)CC2)CC1 Show InChI InChI=1S/C29H33ClN6/c30-26-9-11-27(12-10-26)34-17-13-33(14-18-34)23-25-21-31-36-28(25)7-4-8-29(36)35-19-15-32(16-20-35)22-24-5-2-1-3-6-24/h1-12,21H,13-20,22-23H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D4 stably expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109949 (7-(4-Benzyl-piperazin-1-yl)-3-[4-(4-chloro-phenyl)...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cnn3c(cccc23)N2CCN(Cc3ccccc3)CC2)CC1 Show InChI InChI=1S/C29H33ClN6/c30-26-9-11-27(12-10-26)34-17-13-33(14-18-34)23-25-21-31-36-28(25)7-4-8-29(36)35-19-15-32(16-20-35)22-24-5-2-1-3-6-24/h1-12,21H,13-20,22-23H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D2 (long) stably expressed in CHO cells by [3H]-Spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50109949 (7-(4-Benzyl-piperazin-1-yl)-3-[4-(4-chloro-phenyl)...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cnn3c(cccc23)N2CCN(Cc3ccccc3)CC2)CC1 Show InChI InChI=1S/C29H33ClN6/c30-26-9-11-27(12-10-26)34-17-13-33(14-18-34)23-25-21-31-36-28(25)7-4-8-29(36)35-19-15-32(16-20-35)22-24-5-2-1-3-6-24/h1-12,21H,13-20,22-23H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D3 stably expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109949 (7-(4-Benzyl-piperazin-1-yl)-3-[4-(4-chloro-phenyl)...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cnn3c(cccc23)N2CCN(Cc3ccccc3)CC2)CC1 Show InChI InChI=1S/C29H33ClN6/c30-26-9-11-27(12-10-26)34-17-13-33(14-18-34)23-25-21-31-36-28(25)7-4-8-29(36)35-19-15-32(16-20-35)22-24-5-2-1-3-6-24/h1-12,21H,13-20,22-23H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D2 (long) stably expressed in CHO cells by [3H]-Spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
DRD1 (BOVINE)	BDBM50109949 (7-(4-Benzyl-piperazin-1-yl)-3-[4-(4-chloro-phenyl)...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cnn3c(cccc23)N2CCN(Cc3ccccc3)CC2)CC1 Show InChI InChI=1S/C29H33ClN6/c30-26-9-11-27(12-10-26)34-17-13-33(14-18-34)23-25-21-31-36-28(25)7-4-8-29(36)35-19-15-32(16-20-35)22-24-5-2-1-3-6-24/h1-12,21H,13-20,22-23H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D1 stably expressed in CHO cells by [3H]-SCH- 23390 displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair