BDBM50109954 (3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyrazolo[1,5-a]pyridin-6-yl)methanol::CHEMBL345357::{3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridin-6-yl}-methanol

SMILES: OCc1ccc2c(CN3CCN(CC3)c3ccc(Cl)cc3)cnn2c1

InChI Key: InChIKey=SAPCLYRXCUDCRV-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50109954   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50109954 ((3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyr...) Show SMILES OCc1ccc2c(CN3CCN(CC3)c3ccc(Cl)cc3)cnn2c1 Show InChI InChI=1S/C19H21ClN4O/c20-17-2-4-18(5-3-17)23-9-7-22(8-10-23)13-16-11-21-24-12-15(14-25)1-6-19(16)24/h1-6,11-12,25H,7-10,13-14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D4 stably expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
DRD1 (BOVINE)	BDBM50109954 ((3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyr...) Show SMILES OCc1ccc2c(CN3CCN(CC3)c3ccc(Cl)cc3)cnn2c1 Show InChI InChI=1S/C19H21ClN4O/c20-17-2-4-18(5-3-17)23-9-7-22(8-10-23)13-16-11-21-24-12-15(14-25)1-6-19(16)24/h1-6,11-12,25H,7-10,13-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D1 stably expressed in CHO cells by [3H]-SCH- 23390 displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50109954 ((3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyr...) Show SMILES OCc1ccc2c(CN3CCN(CC3)c3ccc(Cl)cc3)cnn2c1 Show InChI InChI=1S/C19H21ClN4O/c20-17-2-4-18(5-3-17)23-9-7-22(8-10-23)13-16-11-21-24-12-15(14-25)1-6-19(16)24/h1-6,11-12,25H,7-10,13-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D3 stably expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109954 ((3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyr...) Show SMILES OCc1ccc2c(CN3CCN(CC3)c3ccc(Cl)cc3)cnn2c1 Show InChI InChI=1S/C19H21ClN4O/c20-17-2-4-18(5-3-17)23-9-7-22(8-10-23)13-16-11-21-24-12-15(14-25)1-6-19(16)24/h1-6,11-12,25H,7-10,13-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D2 (short) stably expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109954 ((3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyr...) Show SMILES OCc1ccc2c(CN3CCN(CC3)c3ccc(Cl)cc3)cnn2c1 Show InChI InChI=1S/C19H21ClN4O/c20-17-2-4-18(5-3-17)23-9-7-22(8-10-23)13-16-11-21-24-12-15(14-25)1-6-19(16)24/h1-6,11-12,25H,7-10,13-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D2 (long) stably expressed in CHO cells by [3H]-Spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair