null

SMILES: Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)N1CCN(Cc2ccccc2)CC1

InChI Key: InChIKey=OHHKPQVUUXXVGV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50109955   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50109955 (7-(4-Benzyl-piperazin-1-yl)-3-[4-(4-chloro-phenyl)...) Show SMILES Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)N1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C30H35ClN6/c1-24-28(23-34-14-18-35(19-15-34)27-12-10-26(31)11-13-27)29-8-5-9-30(37(29)32-24)36-20-16-33(17-21-36)22-25-6-3-2-4-7-25/h2-13H,14-23H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D4 stably expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109955 (7-(4-Benzyl-piperazin-1-yl)-3-[4-(4-chloro-phenyl)...) Show SMILES Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)N1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C30H35ClN6/c1-24-28(23-34-14-18-35(19-15-34)27-12-10-26(31)11-13-27)29-8-5-9-30(37(29)32-24)36-20-16-33(17-21-36)22-25-6-3-2-4-7-25/h2-13H,14-23H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D2 (short) stably expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50109955 (7-(4-Benzyl-piperazin-1-yl)-3-[4-(4-chloro-phenyl)...) Show SMILES Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)N1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C30H35ClN6/c1-24-28(23-34-14-18-35(19-15-34)27-12-10-26(31)11-13-27)29-8-5-9-30(37(29)32-24)36-20-16-33(17-21-36)22-25-6-3-2-4-7-25/h2-13H,14-23H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D3 stably expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109955 (7-(4-Benzyl-piperazin-1-yl)-3-[4-(4-chloro-phenyl)...) Show SMILES Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)N1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C30H35ClN6/c1-24-28(23-34-14-18-35(19-15-34)27-12-10-26(31)11-13-27)29-8-5-9-30(37(29)32-24)36-20-16-33(17-21-36)22-25-6-3-2-4-7-25/h2-13H,14-23H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D2 (long) stably expressed in CHO cells by [3H]-Spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (BOVINE)	BDBM50109955 (7-(4-Benzyl-piperazin-1-yl)-3-[4-(4-chloro-phenyl)...) Show SMILES Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)N1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C30H35ClN6/c1-24-28(23-34-14-18-35(19-15-34)27-12-10-26(31)11-13-27)29-8-5-9-30(37(29)32-24)36-20-16-33(17-21-36)22-25-6-3-2-4-7-25/h2-13H,14-23H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D1 stably expressed in CHO cells by [3H]-SCH- 23390 displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair