BDBM50109956 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-(4-fluoro-phenyl)-pyrazolo[1,5-a]pyridine::CHEMBL156198

SMILES: Fc1ccc(cc1)-c1cccc2c(CN3CCN(CC3)c3ccc(Cl)cc3)cnn12

InChI Key: InChIKey=LAZCWDPLJFPPDI-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50109956   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50109956 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-(4-...) Show SMILES Fc1ccc(cc1)-c1cccc2c(CN3CCN(CC3)c3ccc(Cl)cc3)cnn12 Show InChI InChI=1S/C24H22ClFN4/c25-20-6-10-22(11-7-20)29-14-12-28(13-15-29)17-19-16-27-30-23(2-1-3-24(19)30)18-4-8-21(26)9-5-18/h1-11,16H,12-15,17H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D4 stably expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50109956 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-(4-...) Show SMILES Fc1ccc(cc1)-c1cccc2c(CN3CCN(CC3)c3ccc(Cl)cc3)cnn12 Show InChI InChI=1S/C24H22ClFN4/c25-20-6-10-22(11-7-20)29-14-12-28(13-15-29)17-19-16-27-30-23(2-1-3-24(19)30)18-4-8-21(26)9-5-18/h1-11,16H,12-15,17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D3 stably expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (BOVINE)	BDBM50109956 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-(4-...) Show SMILES Fc1ccc(cc1)-c1cccc2c(CN3CCN(CC3)c3ccc(Cl)cc3)cnn12 Show InChI InChI=1S/C24H22ClFN4/c25-20-6-10-22(11-7-20)29-14-12-28(13-15-29)17-19-16-27-30-23(2-1-3-24(19)30)18-4-8-21(26)9-5-18/h1-11,16H,12-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D1 stably expressed in CHO cells by [3H]-SCH- 23390 displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109956 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-(4-...) Show SMILES Fc1ccc(cc1)-c1cccc2c(CN3CCN(CC3)c3ccc(Cl)cc3)cnn12 Show InChI InChI=1S/C24H22ClFN4/c25-20-6-10-22(11-7-20)29-14-12-28(13-15-29)17-19-16-27-30-23(2-1-3-24(19)30)18-4-8-21(26)9-5-18/h1-11,16H,12-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D2 (short) stably expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109956 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-(4-...) Show SMILES Fc1ccc(cc1)-c1cccc2c(CN3CCN(CC3)c3ccc(Cl)cc3)cnn12 Show InChI InChI=1S/C24H22ClFN4/c25-20-6-10-22(11-7-20)29-14-12-28(13-15-29)17-19-16-27-30-23(2-1-3-24(19)30)18-4-8-21(26)9-5-18/h1-11,16H,12-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D2 (long) stably expressed in CHO cells by [3H]-Spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
					More data for this Ligand-Target Pair