BDBM50110061 2-chloro-4-[1-[4-(4-isopropylbenzyloxy)-3,5-dimethoxyphenyl]-(E)-methylideneaminosulfonamido]phenol::CHEMBL158886

SMILES: COc1cc(\C=N\NS(=O)(=O)c2ccc(O)c(Cl)c2)cc(OC)c1OCc1ccc(cc1)C(C)C

InChI Key: InChIKey=JDGCVZKTMKYKFW-MZJWZYIUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50110061   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50110061 (2-chloro-4-[1-[4-(4-isopropylbenzyloxy)-3,5-dimeth...) Show SMILES COc1cc(\C=N\NS(=O)(=O)c2ccc(O)c(Cl)c2)cc(OC)c1OCc1ccc(cc1)C(C)C Show InChI InChI=1S/C25H27ClN2O6S/c1-16(2)19-7-5-17(6-8-19)15-34-25-23(32-3)11-18(12-24(25)33-4)14-27-28-35(30,31)20-9-10-22(29)21(26)13-20/h5-14,16,28-29H,15H2,1-4H3/b27-14+	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	7.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description In vitro inhibitory activity against human glucagon receptor using [127I]-labeled glucagon				Bioorg Med Chem Lett 12: 663-6 (2002) BindingDB Entry DOI: 10.7270/Q2J67G77
					More data for this Ligand-Target Pair