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SMILES: C[C@H](CNCCCCc1cccc2ncccc12)c1c([nH]c2ccc(cc12)C(C)(C)C(=O)N1C2CCC1CC2)-c1cc(C)cc(C)c1

InChI Key: InChIKey=OREBMADZDPBHSM-KZZSTRQFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110615   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50110615 (1-(7-Aza-bicyclo[2.2.1]hept-7-yl)-2-{2-(3,5-dimeth...) Show SMILES C[C@H](CNCCCCc1cccc2ncccc12)c1c([nH]c2ccc(cc12)C(C)(C)C(=O)N1C2CCC1CC2)-c1cc(C)cc(C)c1 |TLB:30:32:37.38:34.35| Show InChI InChI=1S/C42H50N4O/c1-27-22-28(2)24-31(23-27)40-39(29(3)26-43-20-7-6-10-30-11-8-13-37-35(30)12-9-21-44-37)36-25-32(14-19-38(36)45-40)42(4,5)41(47)46-33-15-16-34(46)18-17-33/h8-9,11-14,19,21-25,29,33-34,43,45H,6-7,10,15-18,20,26H2,1-5H3/t29-,33?,34?/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of gonadotropin-releasing hormone receptor-stimulated [3H]-inositol phosphate hydrolysis				Bioorg Med Chem Lett 12: 827-32 (2002) BindingDB Entry DOI: 10.7270/Q2G73D1X
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50110615 (1-(7-Aza-bicyclo[2.2.1]hept-7-yl)-2-{2-(3,5-dimeth...) Show SMILES C[C@H](CNCCCCc1cccc2ncccc12)c1c([nH]c2ccc(cc12)C(C)(C)C(=O)N1C2CCC1CC2)-c1cc(C)cc(C)c1 |TLB:30:32:37.38:34.35| Show InChI InChI=1S/C42H50N4O/c1-27-22-28(2)24-31(23-27)40-39(29(3)26-43-20-7-6-10-30-11-8-13-37-35(30)12-9-21-44-37)36-25-32(14-19-38(36)45-40)42(4,5)41(47)46-33-15-16-34(46)18-17-33/h8-9,11-14,19,21-25,29,33-34,43,45H,6-7,10,15-18,20,26H2,1-5H3/t29-,33?,34?/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-buserelin binding to human pituitary gonadotropin-releasing hormone receptor				Bioorg Med Chem Lett 12: 827-32 (2002) BindingDB Entry DOI: 10.7270/Q2G73D1X
					More data for this Ligand-Target Pair