BDBM50111305 8-{4-[(4-Hydroxy-5-nitro-2-oxo-1,2-dihydro-quinoline-3-carbonyl)-amino]-phenoxy}-octanoic acid::CHEMBL10543

SMILES: OC(=O)CCCCCCCOc1ccc(NC(=O)c2c(O)c3c(cccc3[nH]c2=O)[N+]([O-])=O)cc1

InChI Key: InChIKey=RVAUDRRVJOFJJT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50111305   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen activator inhibitor-1 (Homo sapiens (Human))	BDBM50111305 (8-{4-[(4-Hydroxy-5-nitro-2-oxo-1,2-dihydro-quinoli...) Show SMILES OC(=O)CCCCCCCOc1ccc(NC(=O)c2c(O)c3c(cccc3[nH]c2=O)[N+]([O-])=O)cc1 Show InChI InChI=1S/C24H25N3O8/c28-19(29)9-4-2-1-3-5-14-35-16-12-10-15(11-13-16)25-23(31)21-22(30)20-17(26-24(21)32)7-6-8-18(20)27(33)34/h6-8,10-13H,1-5,9,14H2,(H,25,31)(H,28,29)(H2,26,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenova Limited Curated by ChEMBL					Assay Description Inhibitory activity against human plasminogen activator inhibitor-1(PAI-1) evaluated by chromogenic assay.				Bioorg Med Chem Lett 12: 1063-6 (2002) BindingDB Entry DOI: 10.7270/Q2W958HQ
					More data for this Ligand-Target Pair