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BDBM50112044 4-Amino-N-{1-[1-(2-amino-acetyl)-piperidin-4-ylmethyl]-piperidin-4-yl}-5-chloro-2-methoxy-benzamide::CHEMBL172314

SMILES: COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCN(CC2)C(=O)CN)CC1

InChI Key: InChIKey=OFBHDACDYTWWDF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50112044   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
HTR4


(GUINEA PIG)		BDBM50112044
PNG
(4-Amino-N-{1-[1-(2-amino-acetyl)-piperidin-4-ylmet...)
Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCN(CC2)C(=O)CN)CC1
Show InChI InChI=1S/C21H32ClN5O3/c1-30-19-11-18(24)17(22)10-16(19)21(29)25-15-4-6-26(7-5-15)13-14-2-8-27(9-3-14)20(28)12-23/h10-11,14-15H,2-9,12-13,23-24H2,1H3,(H,25,29)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 9.30n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-hydroxytryptamine 4 receptor of guinea pig striatum using [3H]-GR-113,808 as radioligand

Bioorg Med Chem Lett 12: 967-70 (2002)


BindingDB Entry DOI: 10.7270/Q2RF5TB7
More data for this
Ligand-Target Pair