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BDBM50112045 4-Amino-N-{1-[1-(3-amino-2-methyl-propionyl)-piperidin-4-ylmethyl]-piperidin-4-yl}-5-chloro-2-methoxy-benzamide::CHEMBL425329

SMILES: COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCN(CC2)C(=O)C(C)CN)CC1

InChI Key: InChIKey=XKKCRENQKGZPBL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50112045   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
HTR4


(GUINEA PIG)		BDBM50112045
PNG
(4-Amino-N-{1-[1-(3-amino-2-methyl-propionyl)-piper...)
Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCN(CC2)C(=O)C(C)CN)CC1
Show InChI InChI=1S/C23H36ClN5O3/c1-15(13-25)23(31)29-9-3-16(4-10-29)14-28-7-5-17(6-8-28)27-22(30)18-11-19(24)20(26)12-21(18)32-2/h11-12,15-17H,3-10,13-14,25-26H2,1-2H3,(H,27,30)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 5.10n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-hydroxytryptamine 4 receptor of guinea pig striatum using [3H]-GR-113,808 as radioligand

Bioorg Med Chem Lett 12: 967-70 (2002)


BindingDB Entry DOI: 10.7270/Q2RF5TB7
More data for this
Ligand-Target Pair