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BDBM50112046 4-Amino-N-{1-[1-(5-amino-pentanoyl)-piperidin-4-ylmethyl]-piperidin-4-yl}-5-chloro-2-methoxy-benzamide::CHEMBL173089

SMILES: COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCN(CC2)C(=O)CCCCN)CC1

InChI Key: InChIKey=QULCWFARQJYIIV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50112046   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
HTR4


(GUINEA PIG)		BDBM50112046
PNG
(4-Amino-N-{1-[1-(5-amino-pentanoyl)-piperidin-4-yl...)
Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCN(CC2)C(=O)CCCCN)CC1
Show InChI InChI=1S/C24H38ClN5O3/c1-33-22-15-21(27)20(25)14-19(22)24(32)28-18-7-10-29(11-8-18)16-17-5-12-30(13-6-17)23(31)4-2-3-9-26/h14-15,17-18H,2-13,16,26-27H2,1H3,(H,28,32)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 3.90n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-hydroxytryptamine 4 receptor of guinea pig striatum using [3H]-GR-113,808 as radioligand

Bioorg Med Chem Lett 12: 967-70 (2002)


BindingDB Entry DOI: 10.7270/Q2RF5TB7
More data for this
Ligand-Target Pair