BDBM50112649 4-[(7-Bromo-naphthalene-2-carbonyl)-amino]-5-(2-oxo-pyrrolidin-3-yl)-pent-2-enoic acid ethyl ester::CHEMBL62353

SMILES: CCOC(=O)\C=C\[C@H](C[C@@H]1CCNC1=O)NC(=O)c1ccc2ccc(Br)cc2c1

InChI Key: InChIKey=VUJUKPADIHZTDG-BOYOMHKPSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50112649   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human rhinovirus A protease (Human rhinovirus B)	BDBM50112649 (4-[(7-Bromo-naphthalene-2-carbonyl)-amino]-5-(2-ox...) Show SMILES CCOC(=O)\C=C\[C@H](C[C@@H]1CCNC1=O)NC(=O)c1ccc2ccc(Br)cc2c1 Show InChI InChI=1S/C22H23BrN2O4/c1-2-29-20(26)8-7-19(13-16-9-10-24-21(16)27)25-22(28)15-4-3-14-5-6-18(23)12-17(14)11-15/h3-8,11-12,16,19H,2,9-10,13H2,1H3,(H,24,27)(H,25,28)/b8-7+/t16-,19+/m0/s1	MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	180	n/a	n/a	n/a	n/a
Pfizer Global R&D-La Jolla/Agouron Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Human Rhinovirus 14 (HRV14) Protease 3C				J Med Chem 45: 2016-23 (2002) BindingDB Entry DOI: 10.7270/Q289156B
					More data for this Ligand-Target Pair