BDBM50112653 4-[(2H-Chromene-3-carbonyl)-amino]-5-(2-oxo-pyrrolidin-3-yl)-pent-2-enoic acid ethyl ester::4S-[(2H-Chromene-3-carbonyl)amino]-5-(2-oxopyrrolidin-3S-yl)pent-2-enoic Acid Ethyl Ester::CHEMBL292942

SMILES: CCOC(=O)\C=C\[C@H](C[C@@H]1CCNC1=O)NC(=O)C1=Cc2ccccc2OC1

InChI Key: InChIKey=SJQVINWPPHUDDQ-CRLUXQHQSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50112653   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human rhinovirus A protease (Human rhinovirus B)	BDBM50112653 (4-[(2H-Chromene-3-carbonyl)-amino]-5-(2-oxo-pyrrol...) Show SMILES CCOC(=O)\C=C\[C@H](C[C@@H]1CCNC1=O)NC(=O)C1=Cc2ccccc2OC1 |r,t:19| Show InChI InChI=1S/C21H24N2O5/c1-2-27-19(24)8-7-17(12-15-9-10-22-20(15)25)23-21(26)16-11-14-5-3-4-6-18(14)28-13-16/h3-8,11,15,17H,2,9-10,12-13H2,1H3,(H,22,25)(H,23,26)/b8-7+/t15-,17+/m0/s1	MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a
Pfizer Global R&D-La Jolla/Agouron Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Human Rhinovirus 14 (HRV14) Protease 3C				J Med Chem 45: 2016-23 (2002) BindingDB Entry DOI: 10.7270/Q289156B
					More data for this Ligand-Target Pair