BDBM50112952 4-(2,6-Dimethyl-phenyl)-imidazo[1,5-a]quinoxaline::4-(2,6-dimethylphenyl)imidazo[1,5-a]quinoxaline::CHEMBL30250

SMILES: Cc1cccc(C)c1-c1nc2ccccc2n2cncc12

InChI Key: InChIKey=ZPRRIUIBOLATFJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50112952   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50112952 (4-(2,6-Dimethyl-phenyl)-imidazo[1,5-a]quinoxaline ...) Show SMILES Cc1cccc(C)c1-c1nc2ccccc2n2cncc12 |(10.14,-7.28,;11.48,-6.52,;12.82,-7.3,;14.17,-6.53,;14.17,-4.97,;12.84,-4.19,;12.84,-2.66,;11.49,-4.97,;10.16,-4.18,;8.81,-4.95,;7.49,-4.18,;6.16,-4.95,;4.83,-4.18,;4.83,-2.64,;6.16,-1.87,;7.49,-2.64,;8.81,-1.87,;9.14,-.37,;10.67,-.22,;11.31,-1.61,;10.16,-2.64,)| Show InChI InChI=1S/C18H15N3/c1-12-6-5-7-13(2)17(12)18-16-10-19-11-21(16)15-9-4-3-8-14(15)20-18/h3-11H,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Zurich Curated by ChEMBL					Assay Description Inhibition of Lck				J Med Chem 51: 1179-88 (2008) Article DOI: 10.1021/jm070654j BindingDB Entry DOI: 10.7270/Q29Z95RD
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50112952 (4-(2,6-Dimethyl-phenyl)-imidazo[1,5-a]quinoxaline ...) Show SMILES Cc1cccc(C)c1-c1nc2ccccc2n2cncc12 |(10.14,-7.28,;11.48,-6.52,;12.82,-7.3,;14.17,-6.53,;14.17,-4.97,;12.84,-4.19,;12.84,-2.66,;11.49,-4.97,;10.16,-4.18,;8.81,-4.95,;7.49,-4.18,;6.16,-4.95,;4.83,-4.18,;4.83,-2.64,;6.16,-1.87,;7.49,-2.64,;8.81,-1.87,;9.14,-.37,;10.67,-.22,;11.31,-1.61,;10.16,-2.64,)| Show InChI InChI=1S/C18H15N3/c1-12-6-5-7-13(2)17(12)18-16-10-19-11-21(16)15-9-4-3-8-14(15)20-18/h3-11H,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against recombinant p56 Lck tyrosine kinase expressed as a His-tagged protein in insect cells using a baculovirus expression syst...				Bioorg Med Chem Lett 12: 1361-4 (2002) BindingDB Entry DOI: 10.7270/Q2R78DJ1
					More data for this Ligand-Target Pair