BDBM50113117 1-((E)-2-Phenyl-ethenesulfonyl)-piperidine-2-carboxylic acid benzylamide::CHEMBL291230

SMILES: O=C(NCc1ccccc1)C1CCCCN1S(=O)(=O)\C=C\c1ccccc1

InChI Key: InChIKey=LDLXZRFUPMBAFD-JQIJEIRASA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50113117   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50113117 (1-((E)-2-Phenyl-ethenesulfonyl)-piperidine-2-carbo...) Show SMILES O=C(NCc1ccccc1)C1CCCCN1S(=O)(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C21H24N2O3S/c24-21(22-17-19-11-5-2-6-12-19)20-13-7-8-15-23(20)27(25,26)16-14-18-9-3-1-4-10-18/h1-6,9-12,14,16,20H,7-8,13,15,17H2,(H,22,24)/b16-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Ability to inhibit peptidyl-prolyl isomerase (PPIase, or rotamase) activity of FK506 binding protein 12				Bioorg Med Chem Lett 12: 1429-33 (2002) BindingDB Entry DOI: 10.7270/Q23J3C9S
					More data for this Ligand-Target Pair