BDBM50114689 CHEMBL3609657
SMILES: [H][C@@]12C[C@H](O)CCN1C(=O)c1cccc(NC(=O)Nc3cnccn3)c21
InChI Key: InChIKey=PFDVIMSWMQLRQB-MFKMUULPSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human)) | BDBM50114689 (CHEMBL3609657) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 7311 Curated by ChEMBL | Assay Description Inhibition of human recombinant GST-tagged DYRK1A expressed in Escherichia coli | Eur J Med Chem 101: 274-87 (2015) BindingDB Entry DOI: 10.7270/Q24T6M53 | |||||||||||
More data for this Ligand-Target Pair |