BDBM50114767 2-Chloro-3-(2-pyridin-3-yl-vinyl)-5-(pyrrolidin-2-ylmethoxy)-pyridine::CHEMBL316539

SMILES: Clc1ncc(OCC2CCCN2)cc1\C=C\c1cccnc1

InChI Key: InChIKey=LDMDYPWUDDFQHB-AATRIKPKSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50114767   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50114767 (2-Chloro-3-(2-pyridin-3-yl-vinyl)-5-(pyrrolidin-2-...) Show SMILES Clc1ncc(OCC2CCCN2)cc1\C=C\c1cccnc1 Show InChI InChI=1S/C17H18ClN3O/c18-17-14(6-5-13-3-1-7-19-10-13)9-16(11-21-17)22-12-15-4-2-8-20-15/h1,3,5-7,9-11,15,20H,2,4,8,12H2/b6-5+	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse Curated by ChEMBL					Assay Description Binding affinity for nAChR with [3H]-imidacloprid in Drosophila				J Med Chem 45: 2841-9 (2002) BindingDB Entry DOI: 10.7270/Q2FN15JT
					More data for this Ligand-Target Pair