BDBM50114782 CHEMBL3609671

SMILES: [H][C@@]12C[C@H](O)CCN1C(=O)c1cccc(NC(=O)Nc3ncccc3C)c21

InChI Key: InChIKey=HGUSGBLHYRXWQF-DOMZBBRYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50114782   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human))	BDBM50114782 (CHEMBL3609671) Show SMILES [H][C@@]12C[C@H](O)CCN1C(=O)c1cccc(NC(=O)Nc3ncccc3C)c21 |r| Show InChI InChI=1S/C19H20N4O3/c1-11-4-3-8-20-17(11)22-19(26)21-14-6-2-5-13-16(14)15-10-12(24)7-9-23(15)18(13)25/h2-6,8,12,15,24H,7,9-10H2,1H3,(H2,20,21,22,26)/t12-,15+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 7311 Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged DYRK1A expressed in Escherichia coli				Eur J Med Chem 101: 274-87 (2015) BindingDB Entry DOI: 10.7270/Q24T6M53
					More data for this Ligand-Target Pair