BDBM50115374 2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-naphthalen-1-yl-propionylamino}-5-guanidino-pentanoic acid [1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide::CHEMBL319922

SMILES: CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

InChI Key: InChIKey=ZJZJSTFJNWUUAH-YRCZKMHPSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50115374   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Mus musculus)	BDBM50115374 (2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...) Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C38H45N11O5/c1-22(50)46-33(18-26-20-42-21-45-26)37(54)49-32(16-24-10-6-9-23-8-2-3-11-27(23)24)36(53)47-30(14-7-15-43-38(40)41)35(52)48-31(34(39)51)17-25-19-44-29-13-5-4-12-28(25)29/h2-6,8-13,19-21,30-33,44H,7,14-18H2,1H3,(H2,39,51)(H,42,45)(H,46,50)(H,47,53)(H,48,52)(H,49,54)(H4,40,41,43)/t30-,31-,32-,33-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Agonist activity to the mouse Melanocortin-4 receptor (mMC4R)				J Med Chem 45: 3073-81 (2002) BindingDB Entry DOI: 10.7270/Q2KK9CHF
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Mus musculus)	BDBM50115374 (2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...) Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C38H45N11O5/c1-22(50)46-33(18-26-20-42-21-45-26)37(54)49-32(16-24-10-6-9-23-8-2-3-11-27(23)24)36(53)47-30(14-7-15-43-38(40)41)35(52)48-31(34(39)51)17-25-19-44-29-13-5-4-12-28(25)29/h2-6,8-13,19-21,30-33,44H,7,14-18H2,1H3,(H2,39,51)(H,42,45)(H,46,50)(H,47,53)(H,48,52)(H,49,54)(H4,40,41,43)/t30-,31-,32-,33-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Agonist activity to the mouse Melanocortin-3 receptor (mMC3R)				J Med Chem 45: 3073-81 (2002) BindingDB Entry DOI: 10.7270/Q2KK9CHF
					More data for this Ligand-Target Pair
Melanocortin receptor 1 (Mus musculus)	BDBM50115374 (2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...) Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C38H45N11O5/c1-22(50)46-33(18-26-20-42-21-45-26)37(54)49-32(16-24-10-6-9-23-8-2-3-11-27(23)24)36(53)47-30(14-7-15-43-38(40)41)35(52)48-31(34(39)51)17-25-19-44-29-13-5-4-12-28(25)29/h2-6,8-13,19-21,30-33,44H,7,14-18H2,1H3,(H2,39,51)(H,42,45)(H,46,50)(H,47,53)(H,48,52)(H,49,54)(H4,40,41,43)/t30-,31-,32-,33-/m0/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.52E+4	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Agonist activity to the mouse Melanocortin-1 receptor (mMC1R)				J Med Chem 45: 3073-81 (2002) BindingDB Entry DOI: 10.7270/Q2KK9CHF
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (MC5R) (Mus musculus (Mouse))	BDBM50115374 (2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...) Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C38H45N11O5/c1-22(50)46-33(18-26-20-42-21-45-26)37(54)49-32(16-24-10-6-9-23-8-2-3-11-27(23)24)36(53)47-30(14-7-15-43-38(40)41)35(52)48-31(34(39)51)17-25-19-44-29-13-5-4-12-28(25)29/h2-6,8-13,19-21,30-33,44H,7,14-18H2,1H3,(H2,39,51)(H,42,45)(H,46,50)(H,47,53)(H,48,52)(H,49,54)(H4,40,41,43)/t30-,31-,32-,33-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Agonist activity towards mouse Melanocortin-5 receptor (mMC5R)				J Med Chem 45: 3073-81 (2002) BindingDB Entry DOI: 10.7270/Q2KK9CHF
					More data for this Ligand-Target Pair