BDBM50115557 4-(4-Chloro-phenyl)-piperidine-3-carboxylic acid methyl ester::CHEMBL323399
SMILES: COC(=O)C1CNCC[C@@H]1c1ccc(Cl)cc1
InChI Key: InChIKey=DXRLHHQCJXYHPB-JHJMLUEUSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Norepinephrine Monoamine transporters (Rattus norvegicus) | BDBM50115557 (4-(4-Chloro-phenyl)-piperidine-3-carboxylic acid m...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Inhibition of high affinity uptake of [3H]NE by norepinephrine transporter in nerve endings obtained from rat brain. | J Med Chem 45: 3161-70 (2002) BindingDB Entry DOI: 10.7270/Q2FT8MR8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50115557 (4-(4-Chloro-phenyl)-piperidine-3-carboxylic acid m...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 279 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Inhibition of high affinity uptake of [3H]-DA by dopamine transporter in nerve endings obtained from rat brain. | J Med Chem 45: 3161-70 (2002) BindingDB Entry DOI: 10.7270/Q2FT8MR8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50115557 (4-(4-Chloro-phenyl)-piperidine-3-carboxylic acid m...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 434 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Inhibition of high affinity uptake of [3H]5-HT by serotonin transporter in nerve endings obtained from rat brain. | J Med Chem 45: 3161-70 (2002) BindingDB Entry DOI: 10.7270/Q2FT8MR8 | |||||||||||
More data for this Ligand-Target Pair |