BindingDB PrimarySearch

BDBM50115856 2-(3-Cyclopentyloxy-2-hydroxy-phenyl)-1H-indole-5-carboxamidine::2-{5-[AMINO(IMINIO)METHYL]-1H-INDOL-2-YL}-6-(CYCLOPENTYLOXY)BENZENOLATE::CHEMBL64579

SMILES: NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(OC2CCCC2)c1O

InChI Key: InChIKey=CFSQPEBVGUSQII-UHFFFAOYSA-N

Data: 5 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50115856
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50115856 (2-(3-Cyclopentyloxy-2-hydroxy-phenyl)-1H-indole-5-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Curated by ChEMBL					Assay Description Inhibition of urokinase-type plasminogen activator				Bioorg Med Chem Lett 12: 2019-22 (2002) BindingDB Entry DOI: 10.7270/Q237782T
Celera Curated by ChEMBL					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50115856 (2-(3-Cyclopentyloxy-2-hydroxy-phenyl)-1H-indole-5-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Curated by ChEMBL					Assay Description Inhibition of plasmin				Bioorg Med Chem Lett 12: 2019-22 (2002) BindingDB Entry DOI: 10.7270/Q237782T
Celera Curated by ChEMBL					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50115856 (2-(3-Cyclopentyloxy-2-hydroxy-phenyl)-1H-indole-5-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Curated by ChEMBL					Assay Description Inhibition of tissue-type plasminogen activator				Bioorg Med Chem Lett 12: 2019-22 (2002) BindingDB Entry DOI: 10.7270/Q237782T
Celera Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50115856 (2-(3-Cyclopentyloxy-2-hydroxy-phenyl)-1H-indole-5-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	990	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Curated by ChEMBL					Assay Description Inhibition of Coagulation factor X				Bioorg Med Chem Lett 12: 2019-22 (2002) BindingDB Entry DOI: 10.7270/Q237782T
Celera Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50115856 (2-(3-Cyclopentyloxy-2-hydroxy-phenyl)-1H-indole-5-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Curated by ChEMBL					Assay Description Inhibition of thrombin				Bioorg Med Chem Lett 12: 2019-22 (2002) BindingDB Entry DOI: 10.7270/Q237782T
Celera Curated by ChEMBL					More data for this Ligand-Target Pair