BDBM50115865 2-{5-[AMINO(IMINIO)METHYL]-6-FLUORO-1H-BENZIMIDAZOL-2-YL}-6-ISOBUTOXYBENZENOLATE::6-Fluoro-2-(2-hydroxy-3-isobutoxy-phenyl)-1H-benzoimidazole-5-carboxamidine::CHEMBL62836

SMILES: CC(C)COc1cccc(-c2nc3cc(F)c(cc3[nH]2)C(N)=N)c1O

InChI Key: InChIKey=NSUDDASMRZSVON-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50115865   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50115865 (2-{5-[AMINO(IMINIO)METHYL]-6-FLUORO-1H-BENZIMIDAZO...) Show SMILES CC(C)COc1cccc(-c2nc3cc(F)c(cc3[nH]2)C(N)=N)c1O Show InChI InChI=1S/C18H19FN4O2/c1-9(2)8-25-15-5-3-4-10(16(15)24)18-22-13-6-11(17(20)21)12(19)7-14(13)23-18/h3-7,9,24H,8H2,1-2H3,(H3,20,21)(H,22,23)	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Curated by ChEMBL					Assay Description Inhibition of urokinase-type plasminogen activator				Bioorg Med Chem Lett 12: 2019-22 (2002) BindingDB Entry DOI: 10.7270/Q237782T
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50115865 (2-{5-[AMINO(IMINIO)METHYL]-6-FLUORO-1H-BENZIMIDAZO...) Show SMILES CC(C)COc1cccc(-c2nc3cc(F)c(cc3[nH]2)C(N)=N)c1O Show InChI InChI=1S/C18H19FN4O2/c1-9(2)8-25-15-5-3-4-10(16(15)24)18-22-13-6-11(17(20)21)12(19)7-14(13)23-18/h3-7,9,24H,8H2,1-2H3,(H3,20,21)(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Curated by ChEMBL					Assay Description Inhibition of plasmin				Bioorg Med Chem Lett 12: 2019-22 (2002) BindingDB Entry DOI: 10.7270/Q237782T
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50115865 (2-{5-[AMINO(IMINIO)METHYL]-6-FLUORO-1H-BENZIMIDAZO...) Show SMILES CC(C)COc1cccc(-c2nc3cc(F)c(cc3[nH]2)C(N)=N)c1O Show InChI InChI=1S/C18H19FN4O2/c1-9(2)8-25-15-5-3-4-10(16(15)24)18-22-13-6-11(17(20)21)12(19)7-14(13)23-18/h3-7,9,24H,8H2,1-2H3,(H3,20,21)(H,22,23)	PDB GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	PubMed	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Curated by ChEMBL					Assay Description Inhibition of thrombin				Bioorg Med Chem Lett 12: 2019-22 (2002) BindingDB Entry DOI: 10.7270/Q237782T
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50115865 (2-{5-[AMINO(IMINIO)METHYL]-6-FLUORO-1H-BENZIMIDAZO...) Show SMILES CC(C)COc1cccc(-c2nc3cc(F)c(cc3[nH]2)C(N)=N)c1O Show InChI InChI=1S/C18H19FN4O2/c1-9(2)8-25-15-5-3-4-10(16(15)24)18-22-13-6-11(17(20)21)12(19)7-14(13)23-18/h3-7,9,24H,8H2,1-2H3,(H3,20,21)(H,22,23)	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	PubMed	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Curated by ChEMBL					Assay Description Inhibition of Coagulation factor X				Bioorg Med Chem Lett 12: 2019-22 (2002) BindingDB Entry DOI: 10.7270/Q237782T
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50115865 (2-{5-[AMINO(IMINIO)METHYL]-6-FLUORO-1H-BENZIMIDAZO...) Show SMILES CC(C)COc1cccc(-c2nc3cc(F)c(cc3[nH]2)C(N)=N)c1O Show InChI InChI=1S/C18H19FN4O2/c1-9(2)8-25-15-5-3-4-10(16(15)24)18-22-13-6-11(17(20)21)12(19)7-14(13)23-18/h3-7,9,24H,8H2,1-2H3,(H3,20,21)(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	PubMed	6.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Curated by ChEMBL					Assay Description Inhibition of tissue-type plasminogen activator				Bioorg Med Chem Lett 12: 2019-22 (2002) BindingDB Entry DOI: 10.7270/Q237782T
					More data for this Ligand-Target Pair