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SMILES: COc1cc(Nc2nc(N)nc(n2)-c2ccccc2)ccc1-c1cnco1

InChI Key: InChIKey=CMBCCZAWOWOXBW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50116131   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Inosine-5'-monophosphate dehydrogenase 2


(Homo sapiens (Human))		BDBM50116131
PNG
(CHEMBL66782 | N-(3-Methoxy-4-oxazol-5-yl-phenyl)-6...)
Show SMILES COc1cc(Nc2nc(N)nc(n2)-c2ccccc2)ccc1-c1cnco1
Show InChI InChI=1S/C19H16N6O2/c1-26-15-9-13(7-8-14(15)16-10-21-11-27-16)22-19-24-17(23-18(20)25-19)12-5-3-2-4-6-12/h2-11H,1H3,(H3,20,22,23,24,25)
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n/an/a 54n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human Inosine-5'-monophosphate dehydrogenase 2

Bioorg Med Chem Lett 12: 2137-40 (2002)


BindingDB Entry DOI: 10.7270/Q2NZ86Z7
More data for this
Ligand-Target Pair