BDBM50116668 4-Methyl-6-propyl-5,6-dihydro-1H-pyridin-(2Z)-ylideneamine::CHEMBL75496
SMILES: CCCC1CC(C)=CC(N)=N1
InChI Key: InChIKey=BFRRSPPCKUKUNO-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nitric Oxide Synthase, inducible (Mus musculus (mouse)) | BDBM50116668 (4-Methyl-6-propyl-5,6-dihydro-1H-pyridin-(2Z)-ylid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Fukui Research Institute Curated by ChEMBL | Assay Description The concentration required for inhibition of Inducible nitric oxide synthase in mouse | Bioorg Med Chem Lett 12: 2291-4 (2002) BindingDB Entry DOI: 10.7270/Q2M32V3P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, endothelial (Homo sapiens (Human)) | BDBM50116668 (4-Methyl-6-propyl-5,6-dihydro-1H-pyridin-(2Z)-ylid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 580 | n/a | n/a | n/a | n/a | n/a | n/a |
Fukui Research Institute Curated by ChEMBL | Assay Description Inhibition of human endothelial Nitric Oxide Synthase expressed in Sf-21 cells | Bioorg Med Chem Lett 12: 2291-4 (2002) BindingDB Entry DOI: 10.7270/Q2M32V3P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, inducible (Homo sapiens (Human)) | BDBM50116668 (4-Methyl-6-propyl-5,6-dihydro-1H-pyridin-(2Z)-ylid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Fukui Research Institute Curated by ChEMBL | Assay Description Concentration required to inhibit human Inducible nitric oxide synthase over expressed in A549 cells | Bioorg Med Chem Lett 12: 2291-4 (2002) BindingDB Entry DOI: 10.7270/Q2M32V3P | |||||||||||
More data for this Ligand-Target Pair |