BDBM50117650 CHEMBL3613638
SMILES: FC(F)(F)c1ccc(cc1)C(=O)Nc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C1CCCC1
InChI Key: InChIKey=RBKXIFTYFRZIND-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily V member 4 (TRPV4) (Homo sapiens (Human)) | BDBM50117650![]() (CHEMBL3613638) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Renovis, Inc. Curated by ChEMBL | Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m... | Bioorg Med Chem Lett 25: 4011-5 (2015) BindingDB Entry DOI: 10.7270/Q2PG1THP | |||||||||||
More data for this Ligand-Target Pair |