BDBM50117696 CHEMBL315974::Thiophene-2-sulfonic acid [3-(3'-methylsulfanyl-biphenyl-2-yl)-propionyl]-amide
SMILES: CSc1cccc(c1)-c1ccccc1CCC(=O)NS(=O)(=O)c1cccs1
InChI Key: InChIKey=SEFQFOATCPAKJW-UHFFFAOYSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor (Homo sapiens (Human)) | BDBM50117696 (CHEMBL315974 | Thiophene-2-sulfonic acid [3-(3'-me...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Binding affinity at human Prostanoid EP3 receptor. | Bioorg Med Chem Lett 12: 2583-6 (2002) BindingDB Entry DOI: 10.7270/Q2QN663S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human)) | BDBM50117696 (CHEMBL315974 | Thiophene-2-sulfonic acid [3-(3'-me...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Binding affinity at human Prostanoid EP4 receptor. | Bioorg Med Chem Lett 12: 2583-6 (2002) BindingDB Entry DOI: 10.7270/Q2QN663S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human)) | BDBM50117696 (CHEMBL315974 | Thiophene-2-sulfonic acid [3-(3'-me...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Binding affinity at human Prostanoid EP1 receptor. | Bioorg Med Chem Lett 12: 2583-6 (2002) BindingDB Entry DOI: 10.7270/Q2QN663S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM50117696 (CHEMBL315974 | Thiophene-2-sulfonic acid [3-(3'-me...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Binding affinity at human Prostanoid EP2 receptor. | Bioorg Med Chem Lett 12: 2583-6 (2002) BindingDB Entry DOI: 10.7270/Q2QN663S | |||||||||||
More data for this Ligand-Target Pair |