BDBM50117876 CHEMBL3612456
SMILES: CCC(=O)NCC1CCc2ccccc2N1
InChI Key: InChIKey=LNNXOIQESMKYBZ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melatonin receptor (Homo sapiens (Human)) | BDBM50117876 (CHEMBL3612456) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Urbino"Carlo Bo" Curated by ChEMBL | Assay Description Displacement of 2-[125I]-Iodomelatonin from human MT1 receptor transfected in CHO cell membranes after 120 mins | J Med Chem 58: 7512-25 (2015) BindingDB Entry DOI: 10.7270/Q20R9R6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor (Homo sapiens (Human)) | BDBM50117876 (CHEMBL3612456) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | n/a | 242 | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Urbino"Carlo Bo" Curated by ChEMBL | Assay Description Intrinsic activity at human MT1 receptor transfected in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assay | J Med Chem 58: 7512-25 (2015) BindingDB Entry DOI: 10.7270/Q20R9R6D | |||||||||||
More data for this Ligand-Target Pair |