BDBM50117938 (+)4-(2-{4-[1-butyl-4-chloro-(12R)-3,6,7,12-tetrahydropyrido[2',3':4,5]cyclohepta[e]indol-12-yl]hexahydro-1-pyridinyl}-2-oxoethyl)-1-pyridiniumolate::(-)4-(2-{4-[1-butyl-4-chloro-(12R)-3,6,7,12-tetrahydropyrido[2',3':4,5]cyclohepta[e]indol-12-yl]hexahydro-1-pyridinyl}-2-oxoethyl)-1-pyridiniumolate::CHEMBL126423

SMILES: CCCCc1c[nH]c2c(Cl)cc3CCc4cccnc4[C@H](C4CCN(CC4)C(=O)Cc4cc[n+]([O-])cc4)c3c12

InChI Key: InChIKey=MRUHZKKIIBJWLF-GDLZYMKVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50117938   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) Chain B (Homo sapiens (Human))	BDBM50117938 ((+)4-(2-{4-[1-butyl-4-chloro-(12R)-3,6,7,12-tetrah...) Show SMILES CCCCc1c[nH]c2c(Cl)cc3CCc4cccnc4[C@H](C4CCN(CC4)C(=O)Cc4cc[n+]([O-])cc4)c3c12 Show InChI InChI=1S/C32H35ClN4O2/c1-2-3-5-25-20-35-32-26(33)19-24-8-7-23-6-4-13-34-31(23)29(28(24)30(25)32)22-11-14-36(15-12-22)27(38)18-21-9-16-37(39)17-10-21/h4,6,9-10,13,16-17,19-20,22,29,35H,2-3,5,7-8,11-12,14-15,18H2,1H3/t29-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>180	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-val				J Med Chem 45: 3854-64 (2002) BindingDB Entry DOI: 10.7270/Q2TD9WPB
					More data for this Ligand-Target Pair
Protein Farnesyltransferase (PFT) Chain B (Homo sapiens (Human))	BDBM50117938 ((+)4-(2-{4-[1-butyl-4-chloro-(12R)-3,6,7,12-tetrah...) Show SMILES CCCCc1c[nH]c2c(Cl)cc3CCc4cccnc4[C@H](C4CCN(CC4)C(=O)Cc4cc[n+]([O-])cc4)c3c12 Show InChI InChI=1S/C32H35ClN4O2/c1-2-3-5-25-20-35-32-26(33)19-24-8-7-23-6-4-13-34-31(23)29(28(24)30(25)32)22-11-14-36(15-12-22)27(38)18-21-9-16-37(39)17-10-21/h4,6,9-10,13,16-17,19-20,22,29,35H,2-3,5,7-8,11-12,14-15,18H2,1H3/t29-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-val				J Med Chem 45: 3854-64 (2002) BindingDB Entry DOI: 10.7270/Q2TD9WPB
					More data for this Ligand-Target Pair