BDBM50118050 3-((3-tert-butoxybenzyl)(3-phenoxyphenyl)amino)-1,1,1-trifluoropropan-2-ol::3-[(3-tert-Butoxy-benzyl)-(3-phenoxy-phenyl)-amino]-1,1,1-trifluoro-propan-2-ol::CHEMBL419781

SMILES: CC(C)(C)Oc1cccc(CN(CC(O)C(F)(F)F)c2cccc(Oc3ccccc3)c2)c1

InChI Key: InChIKey=KUHXSXNKGUUNBT-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50118050   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50118050 (3-((3-tert-butoxybenzyl)(3-phenoxyphenyl)amino)-1,...) Show SMILES CC(C)(C)Oc1cccc(CN(CC(O)C(F)(F)F)c2cccc(Oc3ccccc3)c2)c1 Show InChI InChI=1S/C26H28F3NO3/c1-25(2,3)33-23-14-7-9-19(15-23)17-30(18-24(31)26(27,28)29)20-10-8-13-22(16-20)32-21-11-5-4-6-12-21/h4-16,24,31H,17-18H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of cholesteryl ester transfer protein in presence of buffer.				J Med Chem 45: 3891-904 (2002) BindingDB Entry DOI: 10.7270/Q2JW8D7P
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Oryctolagus cuniculus)	BDBM50118050 (3-((3-tert-butoxybenzyl)(3-phenoxyphenyl)amino)-1,...) Show SMILES CC(C)(C)Oc1cccc(CN(CC(O)C(F)(F)F)c2cccc(Oc3ccccc3)c2)c1 Show InChI InChI=1S/C26H28F3NO3/c1-25(2,3)33-23-14-7-9-19(15-23)17-30(18-24(31)26(27,28)29)20-10-8-13-22(16-20)32-21-11-5-4-6-12-21/h4-16,24,31H,17-18H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Al-Zaytoonah Private University of Jordan Curated by ChEMBL					Assay Description Inhibition of CETP in rabbit serum after 1 hr by fluorescent cholesteryl esters transfer assay				Eur J Med Chem 45: 1598-617 (2010) Article DOI: 10.1016/j.ejmech.2009.12.070 BindingDB Entry DOI: 10.7270/Q2VQ32VS
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50118050 (3-((3-tert-butoxybenzyl)(3-phenoxyphenyl)amino)-1,...) Show SMILES CC(C)(C)Oc1cccc(CN(CC(O)C(F)(F)F)c2cccc(Oc3ccccc3)c2)c1 Show InChI InChI=1S/C26H28F3NO3/c1-25(2,3)33-23-14-7-9-19(15-23)17-30(18-24(31)26(27,28)29)20-10-8-13-22(16-20)32-21-11-5-4-6-12-21/h4-16,24,31H,17-18H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal da Bahia Curated by ChEMBL					Assay Description Inhibition of CETP				Bioorg Med Chem 15: 6242-52 (2007) Article DOI: 10.1016/j.bmc.2007.06.021 BindingDB Entry DOI: 10.7270/Q2B857VG
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50118050 (3-((3-tert-butoxybenzyl)(3-phenoxyphenyl)amino)-1,...) Show SMILES CC(C)(C)Oc1cccc(CN(CC(O)C(F)(F)F)c2cccc(Oc3ccccc3)c2)c1 Show InChI InChI=1S/C26H28F3NO3/c1-25(2,3)33-23-14-7-9-19(15-23)17-30(18-24(31)26(27,28)29)20-10-8-13-22(16-20)32-21-11-5-4-6-12-21/h4-16,24,31H,17-18H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Curated by ChEMBL					Assay Description Inhibition of cholesteryl ester transfer protein in presence of human serum				J Med Chem 45: 3891-904 (2002) BindingDB Entry DOI: 10.7270/Q2JW8D7P
					More data for this Ligand-Target Pair