BDBM50118126 CHEMBL3612226

SMILES: O=C(Nc1ccc(cc1)C#N)Nc1ccccc1Sc1ccnc2ccsc12

InChI Key: InChIKey=NHDAFIBNBBHXMS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50118126   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50118126 (CHEMBL3612226) Show SMILES O=C(Nc1ccc(cc1)C#N)Nc1ccccc1Sc1ccnc2ccsc12 Show InChI InChI=1S/C21H14N4OS2/c22-13-14-5-7-15(8-6-14)24-21(26)25-16-3-1-2-4-18(16)28-19-9-11-23-17-10-12-27-20(17)19/h1-12H,(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Minho Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using Tyr1 peptide as substrate after 1 hr by FRET-based assay in presence of 10 uM ATP				Bioorg Med Chem 23: 6497-509 (2015) BindingDB Entry DOI: 10.7270/Q27946G5
					More data for this Ligand-Target Pair