BDBM50118355 (2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithia-4,6-diaza-inden-5-yl)-propyl-amine::CHEMBL133596

SMILES: CCCNC1=Nc2cc(Cl)sc2S(=O)(=O)N1

InChI Key: InChIKey=ZGZLGEKWWVAQMX-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50118355   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118355 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...) Show SMILES CCCNC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:4| Show InChI InChI=1S/C8H10ClN3O2S2/c1-2-3-10-8-11-5-4-6(9)15-7(5)16(13,14)12-8/h4H,2-3H2,1H3,(H2,10,11,12)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118355 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...) Show SMILES CCCNC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:4| Show InChI InChI=1S/C8H10ClN3O2S2/c1-2-3-10-8-11-5-4-6(9)15-7(5)16(13,14)12-8/h4H,2-3H2,1H3,(H2,10,11,12)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.84E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low ...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118355 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...) Show SMILES CCCNC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:4| Show InChI InChI=1S/C8H10ClN3O2S2/c1-2-3-10-8-11-5-4-6(9)15-7(5)16(13,14)12-8/h4H,2-3H2,1H3,(H2,10,11,12)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.24E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair