BDBM50119272 (7-Chloro-1,1-dioxo-1,4-dihydro-1lambda*6*-benzo[1,2,4]thiadiazin-3-yl)-cyclobutyl-amine::(7-Chloro-1,1-dioxo-1,4-dihydro-1lambda*6*-benzo[1,2,4]thiadiazin-3-yl)-cyclobutyl-amine]::CHEMBL318931

SMILES: Clc1ccc2N=C(NC3CCC3)NS(=O)(=O)c2c1

InChI Key: InChIKey=KFNWDGMCTOKMHH-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50119272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 1 (Homo sapiens (Human))	BDBM50119272 ((7-Chloro-1,1-dioxo-1,4-dihydro-1lambda*6*-benzo[1...) Show SMILES Clc1ccc2N=C(NC3CCC3)NS(=O)(=O)c2c1 |t:5| Show InChI InChI=1S/C11H12ClN3O2S/c12-7-4-5-9-10(6-7)18(16,17)15-11(14-9)13-8-2-1-3-8/h4-6,8H,1-3H2,(H2,13,14,15)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Negative log EC50 for Beta-cell KATP channel				Bioorg Med Chem Lett 12: 2977-80 (2002) BindingDB Entry DOI: 10.7270/Q20V8C4M
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 1 (Homo sapiens (Human))	BDBM50119272 ((7-Chloro-1,1-dioxo-1,4-dihydro-1lambda*6*-benzo[1...) Show SMILES Clc1ccc2N=C(NC3CCC3)NS(=O)(=O)c2c1 |t:5| Show InChI InChI=1S/C11H12ClN3O2S/c12-7-4-5-9-10(6-7)18(16,17)15-11(14-9)13-8-2-1-3-8/h4-6,8H,1-3H2,(H2,13,14,15)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	196	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Inhibition of Beta-cell KATP channel				Bioorg Med Chem Lett 12: 2977-80 (2002) BindingDB Entry DOI: 10.7270/Q20V8C4M
					More data for this Ligand-Target Pair