BDBM50119274 CHEMBL100793::Cyclobutyl-(7-nitro-1,1-dioxo-1,4-dihydro-1lambda*6*-benzo[1,2,4]thiadiazin-3-yl)-amine

SMILES: [O-][N+](=O)c1ccc2[N-]\C(NS(=O)(=O)c2c1)=[NH+]\C1CCC1

InChI Key: InChIKey=WCGIBMNFWANOKA-UHFFFAOYSA-O

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50119274   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50119274 (CHEMBL100793 | Cyclobutyl-(7-nitro-1,1-dioxo-1,4-d...) Show SMILES [O-][N+](=O)c1ccc2[N-]\C(NS(=O)(=O)c2c1)=[NH+]\C1CCC1 Show InChI InChI=1S/C11H11N4O4S/c16-15(17)8-4-5-9-10(6-8)20(18,19)14-11(13-9)12-7-2-1-3-7/h4-7H,1-3H2,(H-,12,13,14)/q-1/p+1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	530	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Inhibition of Beta-cell KATP channel				Bioorg Med Chem Lett 12: 2977-80 (2002) BindingDB Entry DOI: 10.7270/Q20V8C4M
					More data for this Ligand-Target Pair