BDBM50119382 CHEMBL344677::N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)H-pyrazolo[1,5-a]pyridine-7-carboxamide::Pyrazolo[1,5-a]pyridine-7-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide

SMILES: COc1ccccc1N1CCN(CCCCNC(=O)c2cccc3ccnn23)CC1

InChI Key: InChIKey=XVKBKIBQGMWRDG-UHFFFAOYSA-N

Data: 8 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50119382   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50119382 (CHEMBL344677 | N-(4-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cccc3ccnn23)CC1 Show InChI InChI=1S/C23H29N5O2/c1-30-22-10-3-2-8-20(22)27-17-15-26(16-18-27)14-5-4-12-24-23(29)21-9-6-7-19-11-13-25-28(19)21/h2-3,6-11,13H,4-5,12,14-18H2,1H3,(H,24,29)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding affinity for human Dopamine receptor D4 by [3H]- spiperone displacement.				J Med Chem 45: 4594-7 (2002) BindingDB Entry DOI: 10.7270/Q2DR2W7K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50119382 (CHEMBL344677 | N-(4-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cccc3ccnn23)CC1 Show InChI InChI=1S/C23H29N5O2/c1-30-22-10-3-2-8-20(22)27-17-15-26(16-18-27)14-5-4-12-24-23(29)21-9-6-7-19-11-13-25-28(19)21/h2-3,6-11,13H,4-5,12,14-18H2,1H3,(H,24,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]- 8-OH-DPAT from porcine 5-hydroxytryptamine 1A receptor				J Med Chem 45: 4594-7 (2002) BindingDB Entry DOI: 10.7270/Q2DR2W7K
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50119382 (CHEMBL344677 | N-(4-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cccc3ccnn23)CC1 Show InChI InChI=1S/C23H29N5O2/c1-30-22-10-3-2-8-20(22)27-17-15-26(16-18-27)14-5-4-12-24-23(29)21-9-6-7-19-11-13-25-28(19)21/h2-3,6-11,13H,4-5,12,14-18H2,1H3,(H,24,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding affinity for human Dopamine receptor D3 by [3H]- spiperone displacement.				J Med Chem 45: 4594-7 (2002) BindingDB Entry DOI: 10.7270/Q2DR2W7K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50119382 (CHEMBL344677 | N-(4-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cccc3ccnn23)CC1 Show InChI InChI=1S/C23H29N5O2/c1-30-22-10-3-2-8-20(22)27-17-15-26(16-18-27)14-5-4-12-24-23(29)21-9-6-7-19-11-13-25-28(19)21/h2-3,6-11,13H,4-5,12,14-18H2,1H3,(H,24,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2L receptor expressed in CHO cell membranes by radioligand competition binding assay				Bioorg Med Chem 23: 6195-209 (2015) BindingDB Entry DOI: 10.7270/Q2WW7KGM
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50119382 (CHEMBL344677 | N-(4-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cccc3ccnn23)CC1 Show InChI InChI=1S/C23H29N5O2/c1-30-22-10-3-2-8-20(22)27-17-15-26(16-18-27)14-5-4-12-24-23(29)21-9-6-7-19-11-13-25-28(19)21/h2-3,6-11,13H,4-5,12,14-18H2,1H3,(H,24,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding affinity for human Dopamine receptor D2 (short) by [3H]- spiperone displacement.				J Med Chem 45: 4594-7 (2002) BindingDB Entry DOI: 10.7270/Q2DR2W7K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50119382 (CHEMBL344677 | N-(4-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cccc3ccnn23)CC1 Show InChI InChI=1S/C23H29N5O2/c1-30-22-10-3-2-8-20(22)27-17-15-26(16-18-27)14-5-4-12-24-23(29)21-9-6-7-19-11-13-25-28(19)21/h2-3,6-11,13H,4-5,12,14-18H2,1H3,(H,24,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding affinity for human Dopamine receptor D2 (long) by [3H]- spiperone displacement.				J Med Chem 45: 4594-7 (2002) BindingDB Entry DOI: 10.7270/Q2DR2W7K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50119382 (CHEMBL344677 | N-(4-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cccc3ccnn23)CC1 Show InChI InChI=1S/C23H29N5O2/c1-30-22-10-3-2-8-20(22)27-17-15-26(16-18-27)14-5-4-12-24-23(29)21-9-6-7-19-11-13-25-28(19)21/h2-3,6-11,13H,4-5,12,14-18H2,1H3,(H,24,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor expressed in HEK293 cell membranes by radioligand competition binding assay				Bioorg Med Chem 23: 6195-209 (2015) BindingDB Entry DOI: 10.7270/Q2WW7KGM
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50119382 (CHEMBL344677 | N-(4-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cccc3ccnn23)CC1 Show InChI InChI=1S/C23H29N5O2/c1-30-22-10-3-2-8-20(22)27-17-15-26(16-18-27)14-5-4-12-24-23(29)21-9-6-7-19-11-13-25-28(19)21/h2-3,6-11,13H,4-5,12,14-18H2,1H3,(H,24,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding affinity for porcine Dopamine receptor D1 by [3H]-SCH- 23390 displacement.				J Med Chem 45: 4594-7 (2002) BindingDB Entry DOI: 10.7270/Q2DR2W7K
					More data for this Ligand-Target Pair