BDBM50119471 1-[1,2-Bis-(4-fluoro-phenyl)-1H-imidazol-4-ylmethyl]-4-(2-ethoxy-phenyl)-piperazine::CHEMBL142147

SMILES: CCOc1ccccc1N1CCN(Cc2cn(c(n2)-c2ccc(F)cc2)-c2ccc(F)cc2)CC1

InChI Key: InChIKey=OUQCDNRPXRIJIM-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119471   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50119471 (1-[1,2-Bis-(4-fluoro-phenyl)-1H-imidazol-4-ylmethy...) Show SMILES CCOc1ccccc1N1CCN(Cc2cn(c(n2)-c2ccc(F)cc2)-c2ccc(F)cc2)CC1 Show InChI InChI=1S/C28H28F2N4O/c1-2-35-27-6-4-3-5-26(27)33-17-15-32(16-18-33)19-24-20-34(25-13-11-23(30)12-14-25)28(31-24)21-7-9-22(29)10-8-21/h3-14,20H,2,15-19H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	51.9	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Sassari Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine 1A receptor fof rat cerebral cortex using [3H]8-OH-DPAT as radioligand				J Med Chem 45: 4655-68 (2002) BindingDB Entry DOI: 10.7270/Q21G0N0M
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50119471 (1-[1,2-Bis-(4-fluoro-phenyl)-1H-imidazol-4-ylmethy...) Show SMILES CCOc1ccccc1N1CCN(Cc2cn(c(n2)-c2ccc(F)cc2)-c2ccc(F)cc2)CC1 Show InChI InChI=1S/C28H28F2N4O/c1-2-35-27-6-4-3-5-26(27)33-17-15-32(16-18-33)19-24-20-34(25-13-11-23(30)12-14-25)28(31-24)21-7-9-22(29)10-8-21/h3-14,20H,2,15-19H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	273	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Sassari Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine 2A receptor of rat cerebral cortex using [3H]ketanserin as radioligand				J Med Chem 45: 4655-68 (2002) BindingDB Entry DOI: 10.7270/Q21G0N0M
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50119471 (1-[1,2-Bis-(4-fluoro-phenyl)-1H-imidazol-4-ylmethy...) Show SMILES CCOc1ccccc1N1CCN(Cc2cn(c(n2)-c2ccc(F)cc2)-c2ccc(F)cc2)CC1 Show InChI InChI=1S/C28H28F2N4O/c1-2-35-27-6-4-3-5-26(27)33-17-15-32(16-18-33)19-24-20-34(25-13-11-23(30)12-14-25)28(31-24)21-7-9-22(29)10-8-21/h3-14,20H,2,15-19H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	268	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Sassari Curated by ChEMBL					Assay Description In vitro binding affinity for Dopamine D2 receptor of rat using [3H]YM-09151 as radioligand				J Med Chem 45: 4655-68 (2002) BindingDB Entry DOI: 10.7270/Q21G0N0M
					More data for this Ligand-Target Pair