null

SMILES: COc1ccc(Cl)cc1-c1nn(C(C)c2ccc(cc2)C(=O)NCCC(O)=O)c2cc(ccc12)-c1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=WPEGCKBIAJARBF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50120322   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50120322 (CHEMBL3616591) Show SMILES COc1ccc(Cl)cc1-c1nn(C(C)c2ccc(cc2)C(=O)NCCC(O)=O)c2cc(ccc12)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C33H27ClF3N3O5/c1-19(20-3-5-22(6-4-20)32(43)38-16-15-30(41)42)40-28-17-23(21-7-11-25(12-8-21)45-33(35,36)37)9-13-26(28)31(39-40)27-18-24(34)10-14-29(27)44-2/h3-14,17-19H,15-16H2,1-2H3,(H,38,43)(H,41,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 25: 4143-7 (2015) BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50120322 (CHEMBL3616591) Show SMILES COc1ccc(Cl)cc1-c1nn(C(C)c2ccc(cc2)C(=O)NCCC(O)=O)c2cc(ccc12)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C33H27ClF3N3O5/c1-19(20-3-5-22(6-4-20)32(43)38-16-15-30(41)42)40-28-17-23(21-7-11-25(12-8-21)45-33(35,36)37)9-13-26(28)31(39-40)27-18-24(34)10-14-29(27)44-2/h3-14,17-19H,15-16H2,1-2H3,(H,38,43)(H,41,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity against human glucagon receptor expressed in CHO cells assessed as reduction in glucagon-induced cAMP production				Bioorg Med Chem Lett 25: 4143-7 (2015) BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair