BDBM50120719 2-Hydroxy-1,3,4,5-tetrahydro-azepino[5,4,3-cd]indol-6-one::CHEMBL343022

SMILES: Oc1[nH]c2cccc3C(=O)NCCc1c23

InChI Key: InChIKey=PNSAGUZOWVWTHK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50120719   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50120719 (2-Hydroxy-1,3,4,5-tetrahydro-azepino[5,4,3-cd]indo...) Show SMILES Oc1[nH]c2cccc3C(=O)NCCc1c23 Show InChI InChI=1S/C11H10N2O2/c14-10-6-2-1-3-8-9(6)7(4-5-12-10)11(15)13-8/h1-3,13,15H,4-5H2,(H,12,14)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).				J Med Chem 45: 4961-74 (2002) BindingDB Entry DOI: 10.7270/Q2T152ZP
					More data for this Ligand-Target Pair