BDBM50120765 1-(7-Methyl-2-phenyl-imidazo[1,2-a][1,3,5]triazin-4-ylamino)-propan-2-one::CHEMBL146234

SMILES: CC(=O)CNc1nc(nc2nc(C)cn12)-c1ccccc1

InChI Key: InChIKey=VGUQKUXXKQGMDW-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50120765   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine A1 receptor (BOVINE)	BDBM50120765 (1-(7-Methyl-2-phenyl-imidazo[1,2-a][1,3,5]triazin-...) Show SMILES CC(=O)CNc1nc(nc2nc(C)cn12)-c1ccccc1 Show InChI InChI=1S/C15H15N5O/c1-10-9-20-14(16-8-11(2)21)18-13(19-15(20)17-10)12-6-4-3-5-7-12/h3-7,9H,8H2,1-2H3,(H,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]-CHA from Adenosine A1 receptor in bovine cortical membranes.				J Med Chem 45: 5030-6 (2002) BindingDB Entry DOI: 10.7270/Q2JH3KHN
					More data for this Ligand-Target Pair
Adenosine A1 receptor (BOVINE)	BDBM50120765 (1-(7-Methyl-2-phenyl-imidazo[1,2-a][1,3,5]triazin-...) Show SMILES CC(=O)CNc1nc(nc2nc(C)cn12)-c1ccccc1 Show InChI InChI=1S/C15H15N5O/c1-10-9-20-14(16-8-11(2)21)18-13(19-15(20)17-10)12-6-4-3-5-7-12/h3-7,9H,8H2,1-2H3,(H,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Chemistry, School of Pharmacy, North-West University, Private Bag X6001, Potchefstroom 2520, South Africa. Curated by ChEMBL					Assay Description Displacement of [3H]CHA from A1 receptor in bovine cortical membrane				Bioorg Med Chem Lett 27: 3963-3967 (2017) Article DOI: 10.1016/j.bmcl.2017.07.071 BindingDB Entry DOI: 10.7270/Q2BZ68J4
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50120765 (1-(7-Methyl-2-phenyl-imidazo[1,2-a][1,3,5]triazin-...) Show SMILES CC(=O)CNc1nc(nc2nc(C)cn12)-c1ccccc1 Show InChI InChI=1S/C15H15N5O/c1-10-9-20-14(16-8-11(2)21)18-13(19-15(20)17-10)12-6-4-3-5-7-12/h3-7,9H,8H2,1-2H3,(H,16,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]- CGS-21,680 from Adenosine A2a receptor in bovine striatal membranes.				J Med Chem 45: 5030-6 (2002) BindingDB Entry DOI: 10.7270/Q2JH3KHN
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50120765 (1-(7-Methyl-2-phenyl-imidazo[1,2-a][1,3,5]triazin-...) Show SMILES CC(=O)CNc1nc(nc2nc(C)cn12)-c1ccccc1 Show InChI InChI=1S/C15H15N5O/c1-10-9-20-14(16-8-11(2)21)18-13(19-15(20)17-10)12-6-4-3-5-7-12/h3-7,9H,8H2,1-2H3,(H,16,17,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [125I]-AB-MECA from Adenosine A3 receptor in bovine cortical membranes in the presence of 20 nM DPCPX.				J Med Chem 45: 5030-6 (2002) BindingDB Entry DOI: 10.7270/Q2JH3KHN
					More data for this Ligand-Target Pair