BDBM50120922 (8-Chloro-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6-yl)-(2-pyridin-2-yl-ethyl)-amine::CHEMBL147473

SMILES: Clc1ccc2Nc3ncccc3N=C(NCCc3ccccn3)c2c1

InChI Key: InChIKey=YJMYAURKALPGQP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50120922   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50120922 ((8-Chloro-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6...) Show SMILES Clc1ccc2Nc3ncccc3N=C(NCCc3ccccn3)c2c1 |t:13| Show InChI InChI=1S/C19H16ClN5/c20-13-6-7-16-15(12-13)18(23-11-8-14-4-1-2-9-21-14)25-17-5-3-10-22-19(17)24-16/h1-7,9-10,12H,8,11H2,(H,22,24)(H,23,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Liège Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes				J Med Chem 45: 5136-49 (2002) BindingDB Entry DOI: 10.7270/Q2571BC1
					More data for this Ligand-Target Pair