BDBM50120924 8-Methyl-6-(4-phenyl-piperazin-1-yl)-11H-benzo[e]pyrido[3,2-b][1,4]diazepine::CHEMBL149949

SMILES: Cc1ccc2Nc3ncccc3N=C(N3CCN(CC3)c3ccccc3)c2c1

InChI Key: InChIKey=LSIKVLMXFWOPEC-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50120924   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50120924 (8-Methyl-6-(4-phenyl-piperazin-1-yl)-11H-benzo[e]p...) Show SMILES Cc1ccc2Nc3ncccc3N=C(N3CCN(CC3)c3ccccc3)c2c1 |t:13| Show InChI InChI=1S/C23H23N5/c1-17-9-10-20-19(16-17)23(26-21-8-5-11-24-22(21)25-20)28-14-12-27(13-15-28)18-6-3-2-4-7-18/h2-11,16H,12-15H2,1H3,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Liège Curated by ChEMBL					Assay Description In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membrane				J Med Chem 45: 5136-49 (2002) BindingDB Entry DOI: 10.7270/Q2571BC1
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50120924 (8-Methyl-6-(4-phenyl-piperazin-1-yl)-11H-benzo[e]p...) Show SMILES Cc1ccc2Nc3ncccc3N=C(N3CCN(CC3)c3ccccc3)c2c1 |t:13| Show InChI InChI=1S/C23H23N5/c1-17-9-10-20-19(16-17)23(26-21-8-5-11-24-22(21)25-20)28-14-12-27(13-15-28)18-6-3-2-4-7-18/h2-11,16H,12-15H2,1H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Liège Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes				J Med Chem 45: 5136-49 (2002) BindingDB Entry DOI: 10.7270/Q2571BC1
					More data for this Ligand-Target Pair