BDBM50120934 (8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-(8-methyl-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6-yl)-amine::CHEMBL148694
SMILES: Cc1ccc2Nc3ncccc3N=C(NC3CC4CCC(C3)N4Cc3ccccc3)c2c1
InChI Key: InChIKey=LIBNJNRMHRQQCZ-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50120934![]() ((8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-(8-methyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Liège Curated by ChEMBL | Assay Description In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membrane | J Med Chem 45: 5136-49 (2002) BindingDB Entry DOI: 10.7270/Q2571BC1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50120934![]() ((8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-(8-methyl-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 131 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Liège Curated by ChEMBL | Assay Description In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes | J Med Chem 45: 5136-49 (2002) BindingDB Entry DOI: 10.7270/Q2571BC1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50120934![]() ((8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-(8-methyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 149 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Liège Curated by ChEMBL | Assay Description In vitro binding affinity at human cloned Dopamine receptor D2L expressed in Sf9 cell membranes | J Med Chem 45: 5136-49 (2002) BindingDB Entry DOI: 10.7270/Q2571BC1 | |||||||||||
More data for this Ligand-Target Pair |