BDBM50120935 (8-Methyl-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6-yl)-(1-methyl-piperidin-4-yl)-amine::CHEMBL347959

SMILES: CN1CCC(CC1)NC1=Nc2cccnc2Nc2ccc(C)cc12

InChI Key: InChIKey=NKNZUUWFOPEUNZ-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50120935   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50120935 ((8-Methyl-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6...) Show SMILES CN1CCC(CC1)NC1=Nc2cccnc2Nc2ccc(C)cc12 |t:9| Show InChI InChI=1S/C19H23N5/c1-13-5-6-16-15(12-13)18(21-14-7-10-24(2)11-8-14)23-17-4-3-9-20-19(17)22-16/h3-6,9,12,14H,7-8,10-11H2,1-2H3,(H,20,22)(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	132	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Liège Curated by ChEMBL					Assay Description In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membrane				J Med Chem 45: 5136-49 (2002) BindingDB Entry DOI: 10.7270/Q2571BC1
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50120935 ((8-Methyl-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6...) Show SMILES CN1CCC(CC1)NC1=Nc2cccnc2Nc2ccc(C)cc12 |t:9| Show InChI InChI=1S/C19H23N5/c1-13-5-6-16-15(12-13)18(21-14-7-10-24(2)11-8-14)23-17-4-3-9-20-19(17)22-16/h3-6,9,12,14H,7-8,10-11H2,1-2H3,(H,20,22)(H,21,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Liège Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes				J Med Chem 45: 5136-49 (2002) BindingDB Entry DOI: 10.7270/Q2571BC1
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50120935 ((8-Methyl-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6...) Show SMILES CN1CCC(CC1)NC1=Nc2cccnc2Nc2ccc(C)cc12 |t:9| Show InChI InChI=1S/C19H23N5/c1-13-5-6-16-15(12-13)18(21-14-7-10-24(2)11-8-14)23-17-4-3-9-20-19(17)22-16/h3-6,9,12,14H,7-8,10-11H2,1-2H3,(H,20,22)(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Liège Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned Dopamine receptor D2L expressed in Sf9 cell membranes				J Med Chem 45: 5136-49 (2002) BindingDB Entry DOI: 10.7270/Q2571BC1
					More data for this Ligand-Target Pair